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IMMUNITION REPORTS BETTER HEALTH EDUCATION THROUGH INFORMATION FRANKLY SPEAKING PUBLISHED NEWSPAPER COLUMNS BY FRANK JORDAN Frank Jordan MBA has contributed to or authored the IMMUNITION REPORTS on various health topics. IMMUNITION REPORTS are independently produced without association to any specific product(s) and distributed free for health education. If you wish to place IMMUNITION REPORTS on your website or to distribute free, email fjordan@hwwshow.com with request details. Statements in IMMUNITION REPORTS have not been evaluated by the Food & Drug Administration. The products mentioned are not intended to diagnose, mitigate, treat, cure or prevent any disease. Also enjoy selected Frankly Speaking articles by Frank Jordan from his long-running Newspaper Column on wide ranging subjects from humor to history - literally hundreds of different subjects in more than 200 articles (only partially reprinted here). Frank Jordan is a Co-Inventor and Researcher on U.S. Patents issued or in review involving the immune response as listed below and an acknowledged health expert, speaker and author; but not a medical doctor. Consult your personal health care professional for treatment of your individual health challenges. Read the important Health Treatment Notice on behalf of Frank Jordan and Associates by clicking on "Your Health."
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Frankly Speaking Articles Index
Research Index - Published, Patent and Medical School Research involving MG Beta Glucan. Research is continuing in 2011 at the University of Nevada School of Medicine - Reno, Dept. of Microbiology, on MG Glucan (beta 1,3/1,6 d glucan) under the direction K. W. Hunter ScD.
Frank M. Jordan is joined with Co-Patent Inventors K.W. Hunter ScD and R.A. Gault PhD from the U. of Nevada, Reno, School of Medicine, Dept of Microbiology, on the following U.S. Patents issued or in application: U.S. Patent 6,474,003 entitled, "Improved Method for Preparing Small Particle Size Glucan in a Dry Material" with F.M. Jordan, K.W. Hunter and R.A. Gault U.S. Patent Application Serial No. 09/707,436 entitled, "Improved Method for Preparing Small Particle Glucan" with F.M. Jordan, K.W. Hunter and R.A. Gault U.S. Patent Application Serial No. 09/707,437 entitled, "Improved Method for Preparing Small Particle Glucan in a Finely Dispersed Powder" with F.M. Jordan, K.W. Hunter and R.A. Gault U.S. Patent Application Serial No. 09/707,582 entitled, "The Use of Beta 1,3 -Glucan-Containing Compositions to Potentiate Immune Responses by Upregulating the Expression of Costimulatory Molecules" with F.M. Jordan, K.W. Hunter and R.A. Gault U.S. Patent Application Serial No. 60/400,377 N-Acetylglucosamine Containing Microparticulate Beta-Glucan for use as a Vaccine Adjuvant & Method of Manufacture & Use, Conjugates of the Adjuvant & Vaccine, & Pharmaceutical Formulation of Such Conjugates" with F.M. Jordan, K.W. Hunter and R.A. Gault Additional Research Adjuvant - Immunizations: Hunter KW Jr, Berner VK, Sura ME; "Conjugation of protein antigen to microparticulate beta-glucan from Saccharomyces cerevisiae: a new adjuvant for intradermal and oral immunizations," Dept of Microbiology and Immunology, U of Nev Sch of Medicine, Reno, NV 89557, USA. Appl Microbiol Biotechnol; PuMed 18677470; Epub Aug 2, 2008: Quote: Applied Microbiology and Biotechnology: Conjugation of protein antigen to microparticulate B-glucan [MG] from Saccharomyces cerevisiae : a new adjuvant for intradermal and oral immunizations, 2008. Report Excerpt: "Our laboratory has prepared and characterized a novel microparticulate beta-glucan (MG)...we hypothesized that MG could serve as a vaccine adjuvant to enhance specific immune responses. ...When used to immunize mice by the intradermal route, these conjugates enhanced the primary IgG antibody response to BSA in a manner comparable to the prototypic complete Freund's adjuvant....These results suggest that protein antigens can be conjugated to MG via a carabondiimide linkage and that these conjugates provide an adjuvant effect for stimulating the antibody response to the protein antigens."
Immunology Letters 98 115–122: IFN-y primes macrophages for enhanced TNF-a expression in response to stimulatory and non-stimulatory amounts of microparticulate B-glucan Immunology Letters 93 71-78: Microparticulate B-glucan upregulates the expression of B7.1, B7.2, B7-H1, but not B7-DC on cultured murine peritoneal macrophages NIH Grant Application - Abstract Excerpt -: Microparticulate Glucan (MG) as a Vaccine Adjuvant U.S. Patent 6,474,003: Method for preparing small particle size glucan in a dry material with extensive research findings on MG Beta GlucanResearch Presentation - Stanford University Western Conference on Immunology : MG Beta Glucan Research Presented at Stanford University at Western Conference on ImmunologyLetters in Applied Microbiology Vol 35, Issue 4, p 267: Preparation of microparticulate B-glucan from Saccharomyces cerevisiae for use in immune potentiation Research Summary Release - Mode of Action of B-Glucan Immunopotentiators : Activation of Immune Defense Against Infectious Disease
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